Over 43 million Americans experience mental illness in a given year–that’s one in five adults and most of them suffer from depression. There’s no easy test to know if mental illness exists, but there are some common signs:
The latest advances in personalized skincare are here – and it’s about time! In the past, great lengths were taken to look healthy and beautiful. The Hollywood actresses from the early-to-mid 1900’s were known to go to extremes in the name of a youthful look. For example, they used intricate facial contraptions to stop facial sagging in order to fight the ravages of aging. The battle of wrinkles, sun damage, and redness is a real one. And the multi-billion dollar beauty industry thrives on the sale of remedies for these conditions.
People love food. It’s a fact, we love to eat. Food and eating can mean so many things—it’s nurturing, pleasurable, fun, communal, comforting. It signifies culture, community, tradition and family. But what is food really all about?
For many Americans, food has become something more than what it is intended to be—nourishment and fuel. Properties of food have been shaped into chemical compounds that may taste good but have little if any nutritional value. Salt, sugar, fat and artificial colors and additives are processed into foods to make them more appealing, have a longer shelf life and cheaper to produce. Some of these foods shouldn’t even be called food at all! In fact, junk food is the opposite of what food should be; whole, real, grown and raised humanely. It may taste good, but it has little to no nutritional value and can add a lot of calories to your daily intake.
A new finding by the Genetic Investigation of Anthropometric Traits, or GIANT, consortium has identified 97 gene regions associated with obesity, tripling the number of such genes previously known.
Despite this strong influence of genes in obesity, the environment can play as strong a part. It is estimated that 40 to 70 percent of the variation in obesity is caused by genetics. The remaining 30 to 60 percent can be attributed to the environment you live in.
There is now clear evidence that variants of genes such as APOA2, FTO, PPARg, FOXO, KLOTHO, DRD4 and others directly interact with micronutrients (or insulin) to regulate differing metabolism effects, and subsequently can tip individuals over to an obesogenic phenotype depending on environmental factors such as type of food consumed or eating behaviors (DRD4).
Pathway Genomics greatly respects and shares the FDA’s concerns about patient safety. We have received a letter from FDA, dated September 21, 2015, requesting certain information regarding the Pathway Genomics CancerIntercept™ Detect testing service. We are carefully considering the concerns of the FDA as stated in their letter, and we will be responding to that letter. We assure that there is physician involvement in the ordering, review and follow-up of CancerIntercept™ testing. We believe that CancerIntercept™ Detect is a laboratory developed test and, as a CLIA and CAP certified clinical laboratory, we are offering it as such. While Pathway Genomics is involved in educating and marketing the tests to physicians and consumers, we do not believe this is a direct-to-consumer model. We believe we have performed appropriate validation of the test as a laboratory developed test, and we are in the process of performing additional studies.
SAN DIEGO – Sept. 10, 2015 – Pathway Genomics, a global precision medical diagnostics company, announced the launch of CancerInterceptTM, its first liquid biopsy, a non-invasive screening test designed for early cancer detection and monitoring, for as low as $299.
SAN DIEGO, Apr 29, 2015 — Mandy Kenyon, MS, RD, CSSD, is Pathway Genomics’ Registered Dietitian and played a major role in developing the customized diet plans that are part of tests such as Pathway Fit. Mandy is available to answer nutrition- and diet-related questions for Pathway’s clients and customers—contact her at firstname.lastname@example.org.
Mandy recently shared a couple of the most common questions she receives in her work as a dietitian, as well as her responses:
Q: I have a healthy diet, no history of heart disease in my family, and I am overweight but not obese—do I really need to exercise?
A: Absolutely. Being overweight (a BMI of 25.0–29.9) can have consequences, such as an increased risk of coronary heart disease, high blood pressure, stroke, and type II diabetes. Exercise can reduce these risks, and may improve both your current and future health by lessening the chance of complications later on.
SAN DIEGO, Apr 17, 2015 — Leslie Ordal, M.Sc., a field genetic counselor at Pathway Genomics, answers some frequently asked questions:
Are all genetic changes harmful?
No. In fact, everyone has genetic changes – it’s why we’re all different. Some genetic changes, called pathogenic variants, can be harmful to an individual, and in some cases, to their children if passed down.
Many other genetic changes; however, are quite common and have no known effect on health – we call these benign variants, and they’re just part of natural human variation. Some genetic changes can even be beneficial, such as those associated with reduced risk for certain diseases like Alzheimer disease.