We also test for drug responses and adverse reactions. We screen for drug metabolism enzymes and transporters that have been linked to harmful reactions with common medical prescriptions, empowering you and your doctor with information that could possibly save your life. Research indicates that there are 106,000 deaths and 2.2 Million serious events caused by adverse drug reactions in the US each year. These drug reactions are responsible for 5-7% of hospital admissions in the US and Europe. Here are examples:

Clopidogrel (Plavix) Researchers have found that patients with variations in a gene called cytochrome P-450 2C19 (CYP2C19) have a greater risk for major adverse cardiovascular events such as death, heart attack, and stroke.

Warfarin : Every day millions of people take warfarin or Coumadin, a powerful drug used to control life threatening conditions. According to the FDA, hemorrhage during warfarin therapy is a leading cause of death in Western countries and related adverse events account for 1 in 10 hospital admissions.

Tamoxifen : Tamoxifen is a medication for the treatment of breast cancer or for people at a high risk of developing breast cancer. Recent research has shown that 7-10% of women with breast cancer may not receive the full medical benefit from taking tamoxifen due to their unique genetic make-up. These women have a version of a gene called Cytochrome P450 2D6, which reduces the effectiveness of tamoxifen and increases their chance of breast cancer recurrence.

What We Test

• Abacavir Hypersensitivity
• Caffeine Metabolism
• Carbamazepine Hypersensitivity
• Clopidrogel Metabolism
• Methotrexate Toxicity
• Statin Induced Myopathy
• Statin protection against myocardial infarction
• Tamoxifen Response
• Warfarin Metabolism